FAQ

Yes. Histamine Intolerance is when there’s too much histamine in the body due to an imbalance between accumulation and degradation. This can be from increased histamine production, histamine-rich or histamine-liberating foods. It leads to the same symptoms as MCAS, and can be a component of MCAS or an isolated issue. It’s not an allergic reaction, but it can mimic one. Mast Cell Activation Disorders, including MCAS, are caused by increased mast cell activation, increased numbers of mast cells, or infiltration of mast cells into organs.

Absolutely! Our website focuses on women because MCAS affects more women than men (90% of cases are women). We welcome everyone!

Yes. However, it’s not always definitive. Serum tryptase is one of those tests—it’s typically elevated only during a flare-up, making it challenging to get a blood sample. Because there are different forms of Mast Cell Disorders, including Mastocytosis, a definitive diagnosis requires a bone marrow biopsy or other organ biopsy (commonly the skin) that shows dense infiltrates of mast cells.

MCAS is generally considered incurable and treatment is focused on symptom management. Treatment response differs per individual; it takes time to determine which treatments will work for you.

MCAS doesn’t go away, there is no cure, and symptoms can return. It is essential to listen to your body and avoid triggers, get enough sleep, stay well-hydrated, manage stress, maintain a clean environment, make sound dietary choices, continue to take any supplements and/or mediations your provider has prescribed for you, and check in with them regularly.